Biological activity of Quinazoline: A Review
نویسندگان
چکیده
Abstract: The aim of this review is to provide an overview of diverse pharmacological activities of quinazoline moiety. Quinazoline are well known and important nitrogen containing heterocyclic compound made chemical formula C8H6N2 and various methods have been worked out for their synthesis. Quinazoline has become a popular topic up of two fused six-membered simple aromatic rings, a benzene ring and a pyrimidine ring having due to its manifold uses. Numerous quinazoline derivatives have been found to possess a broad spectrum of biological activities, which stimulated the research activity in this field. Quinazolines and its derivatives represent one of the most active classes of compounds, which possess wide range of biological activities like anti-bacterial, analgesic, anti-microbial, anti-inflammatory, anticancer, and anti-hypertensive ,antifungal, anti-HIV, antioxidant, analgesic, anticonvulsant, antimalarial, antitumor, anti-tubercular activities. The purpose of this review was to collate literature work reported by researchers on Quinazoline for their various pharmacological activities and also reported recent efforts made on this moiety. (
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